E-cadherin anticorps

N° du produit ABIN1440031

Cet anticorps Chèvre Polyclonal détecte spécifiquement E-cadherin dans WB, IF, IHC (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Porc, Singe, Poulet, Chien, Lapin, Boeuf (Vache), Cheval, Cobaye, Avian, Cat, Âne, Chévre, Hamster et Mouton. Il a été cité dans 3+ publications.

Aperçu rapide pour E-cadherin anticorps (ABIN1440031)

Antigène: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Reactivité: Humain, Souris, Rat, Porc, Singe, Poulet, Chien, Lapin, Boeuf (Vache), Cheval, Cobaye, Avian, Cat, Âne, Chévre, Hamster, Mouton

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp E-cadherin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-E-cadherin anticorps

Fonction: Anti-CDH1

Séquence: YYYDEEGGGE EDQDFDLSQL HRGLDARPEV TRNDVAPTLM SVPRYLPRPA NPDEIGNFID ENLKAADTDP TAPPYDSLLV FDYEGSGSEA ASLSSL

Specificité: Detects endogenous levels of total E-cadherin protein by Western blot in the whole cell lysates (COS-7 and MDCK).

Attributs du produit: E-Cadherin

Purification: Epitope affinity purified

Immunogène: Purified recombinant peptide derived from within residues 750 to 850 of human CDH1 produced in E. coli.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:2,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000

Restrictions: For Research Use only

Stockage

Concentration: 2 mg/mL

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: The antibody solution should be gently mixed before use.

Stock: 4 °C,-20 °C

Stockage commentaire: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Références pour anticorps anti-E-cadherin (ABIN1440031)

Berardinelli, Russo, Canciello, Di Giacinto, Mauro, Nardinocchi, Bove, Solari, Del Basso De Caro, Cavallo, Barboni: "KLHL14 and E-Cadherin Nuclear Co-Expression as Predicting Factor of Nonfunctioning PitNET Invasiveness: Preliminary Study." dans: Journal of clinical medicine, Vol. 13, Issue 15, (2024) (PubMed).

Rapino, Castellucci, Lizzi, Sabatucci, Angelucci, Tortolani, Rossi, DAndrea, Maccarrone: "Modulation of Endocannabinoid-Binding Receptors in Human Neuroblastoma Cells by Tunicamycin." dans: Molecules (Basel, Switzerland), Vol. 24, Issue 7, (2019) (PubMed).

Canciello, Russo, Berardinelli, Bernabò, Muttini, Mattioli, Barboni: "Progesterone prevents epithelial-mesenchymal transition of ovine amniotic epithelial cells and enhances their immunomodulatory properties." dans: Scientific reports, Vol. 7, Issue 1, pp. 3761, (2018) (PubMed).

Détails sur E-cadherin

Antigène: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Autre désignation: CDH1

Sujet:

Goat polyclonal to CDH1. CDH1 is a classical member of the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised consists of 5 cadherin repeats in the extracellular domain, one trans membrane domain, and a and a highly conserved intracellular domain that binds b-catenin and p120-catenin. CDH1 is involved in mechanisms regulating proliferation, mobility and cell-cell adhesions of epithelial cells. Loss of E-cadherin function or expression has been implicated in cancer metastasis and progression.

ARC-1, CAM 120/80, CD324, CDH1, cdhc-A, CDHE, ECAD, E-Cad E-cadherin, Epithelial cadherin, l-cam, LCAM, P09803, P12830 / Q9R0T4, UVO, Uvomorulin, XBcad, XB-cadherin, XTCAD-1 antibody.

Pathways: Signalisation WNT, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation