SYT2 anticorps (N-Term)

N° du produit ABIN1449191

Détail du produit anti-SYT2 anticorps

Antigène: SYT2 (Synaptotagmin II (SYT2))

Épitope: AA 1-20, N-Term

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SYT2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Séquence: MRNIFKRNQE PIVAPATTTA

Specificité: This antibody reacts with Synaptotagmin 2.

Réactivité croisée (Details): Species reactivity (tested):Rat

Immunogène: Synthesized peptide which corresponding to rat synaptotagmin 2 N-terminus (1-20 aa)

Clone: 8G2

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur SYT2

Antigène: SYT2 (Synaptotagmin II (SYT2))

Autre désignation: Synaptotagmin-2 (SYT2 Produits)

Synonymes: anticorps SytII, anticorps RATSYNII, anticorps SYNII, anticorps R74640, anticorps mKIAA4194, anticorps si:ch211-236j4.1, anticorps synaptotagmin 2, anticorps synaptotagmin II, anticorps synaptotagmin IIa, anticorps SYT2, anticorps Syt2, anticorps syt2a, anticorps syt2

Sujet: Synaptotagmins are a family of at least 15 Ca2+-binding, membrane-trafficking proteins that act as calcium sensors regulating neurotransmitter release. Synaptotagamins are expressed in both vesicular and plasma membranes where they are involved in lipid rearrangements required during synaptic vesicle fusion. Synaptotagmins also interact with calcium channels, sodium channels, ß-SNAP, neurexins, and other neural proteins in the absence of Ca2+, suggesting a role in presynaptic functions. Synaptotagmins exhibit differential expression, with synaptotagmins 1-5 expressed primarily in neural and endocrine tissues. Northern blots in murine brain tissue suggest synaptotagmin 1 is primarily expressed in rostral brain regions but has low expression in regions related to motor functions.Synonyms: SYT-2, SYT2, SYTII, Synaptotagmin 2, Synaptotagmin II

Poids moléculaire: 60 kDa

ID gène: 127833

NCBI Accession: NP_001129976

UniProt: Q8N9I0

Pathways: Synaptic Vesicle Exocytosis