TLR4 anticorps (PE)

N° du produit ABIN1449236

L’anticorps Souris Monoclonal anti-TLR4 a été validé pour FACS. Il convient pour détecter TLR4 dans des échantillons de Souris.

Aperçu rapide pour TLR4 anticorps (PE) (ABIN1449236)

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLR4 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: UT15

Détail du produit anti-TLR4 anticorps (PE)

Specificité: This antibody reacts with mouse TLR4/MD-2 complex.

Purification: Protein A agarose

Immunogène: Mouse TLR4/MD-2 transfected Ba/F3 cell

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: 50 tests in 1 mLPBS containing 1 % BSA and 0.09 % NaN3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8 °C.

Détails sur TLR4

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Autre désignation: CD284 / TLR4

Sujet: Toll, a Drosophila receptor molecule with extracellular leucine-rich repeat (LRR), has a role in triggering innate defenses against bacteria or fungi. TLR4 (Toll-like receptor 4) is a member of TLR family, which is human homologue of Toll protei n. It has extracellular LRR and an intracellular signaling domain, which is similar to the type I IL-1 receptor. TLR4 is expressed in subpopulations of cells including myeloid cells, B cells, monocytes, and endothelial cells. Recent studies have suggested that TLR4 might act as a receptor for LPS (lipopolysaccharide). TLR4 alone is not capable of sensing and signaling the presence of LPS, but another molecule MD-2, which is physically associated with TLR4, is required for LPS recognition through TLR4.Synonyms: Toll-like receptor 4

ID gène: 21898

NCBI Accession: NP_067272

UniProt: Q9QUK6

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins