TLR4 anticorps (PE)
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- Antigène Voir toutes TLR4 Anticorps
- TLR4 (Toll-Like Receptor 4 (TLR4))
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Reactivité
- Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TLR4 est conjugé à/à la PE
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Application
- Flow Cytometry (FACS)
- Specificité
- This antibody reacts with mouse TLR4/MD-2 complex.
- Purification
- Protein A agarose
- Immunogène
- Mouse TLR4/MD-2 transfected Ba/F3 cell
- Clone
- UT15
- Isotype
- IgG1
- Top Product
- Discover our top product TLR4 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- 50 tests in 1 mLPBS containing 1 % BSA and 0.09 % NaN3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8 °C.
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- Antigène
- TLR4 (Toll-Like Receptor 4 (TLR4))
- Autre désignation
- CD284 / TLR4 (TLR4 Produits)
- Synonymes
- anticorps ARMD10, anticorps CD284, anticorps TLR-4, anticorps TOLL, anticorps Lps, anticorps Ly87, anticorps Ran/M1, anticorps Rasl2-8, anticorps toll like receptor 4, anticorps toll-like receptor 4, anticorps TLR4, anticorps Tlr4
- Sujet
- Toll, a Drosophila receptor molecule with extracellular leucine-rich repeat (LRR), has a role in triggering innate defenses against bacteria or fungi. TLR4 (Toll-like receptor 4) is a member of TLR family, which is human homologue of Toll protei n. It has extracellular LRR and an intracellular signaling domain, which is similar to the type I IL-1 receptor. TLR4 is expressed in subpopulations of cells including myeloid cells, B cells, monocytes, and endothelial cells. Recent studies have suggested that TLR4 might act as a receptor for LPS (lipopolysaccharide). TLR4 alone is not capable of sensing and signaling the presence of LPS, but another molecule MD-2, which is physically associated with TLR4, is required for LPS recognition through TLR4.Synonyms: Toll-like receptor 4
- ID gène
- 21898
- NCBI Accession
- NP_067272
- UniProt
- Q9QUK6
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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