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CD46 anticorps (FITC)

CD46 Reactivité: Humain FACS Hôte: Souris Monoclonal TGP3 FITC
N° du produit ABIN1449264
  • Antigène Voir toutes CD46 Anticorps
    CD46
    Reactivité
    • 114
    • 39
    • 20
    • 10
    • 10
    • 1
    Humain
    Hôte
    • 84
    • 50
    • 2
    Souris
    Clonalité
    • 73
    • 63
    Monoclonal
    Conjugué
    • 51
    • 17
    • 16
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD46 est conjugé à/à la FITC
    Application
    • 87
    • 78
    • 42
    • 40
    • 33
    • 15
    • 14
    • 14
    • 13
    • 9
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    Protein A agarose
    Immunogène
    Human pancreatic carcinoma cell line (AsPC1)
    Clone
    TGP3
    Isotype
    IgG2a
    Top Product
    Discover our top product CD46 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS containing 1 % BSA and 0.09 % NaN3
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8 °C.
  • Antigène
    CD46
    Autre désignation
    CD46 / MCP (CD46 Produits)
    Synonymes
    anticorps AHUS2, anticorps MCP, anticorps MIC10, anticorps TLX, anticorps TRA2.10, anticorps Mcp, anticorps CD46, anticorps CD46 molecule, anticorps CD46 antigen, complement regulatory protein, anticorps CD46 molecule, complement regulatory protein, anticorps membrane cofactor protein-like, anticorps CD46, anticorps Cd46, anticorps LOC100341359, anticorps LOC103789310
    Sujet
    CD46, also known as membrane cofactor protein (MCP), was first described as a membrane complement regulator that fu nctions as a cofactor with factor I to cleave complement factors C3b and C4b and thereby protect the cell from co mplement attack. In humans, CD46 is expressed on all nuc leated cells. In the rodent animals, its expression is limited only in testis, indicating that the major function of CD46 among different species lies in fertilization. CD46 and other membrane complement regulatory proteins (CD55 and CD59) are frequently overexpressed on cancer cells, possibly as a mechanism for cancer cells to overcome lysis by complement. Several pathogens, including viruses and bacteria (measles virus, human herpesvirus 6, human group B and D adenoviruses, Streptococcus pyogenes , and pathogenic Neisseria species) have been reported to use CD46 for invasion. Recent evidence also indicates that CD 46 signaling events play an important role in linking innate and acquired immune function.Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
    ID gène
    9606
    UniProt
    P15529
    Pathways
    Regulation of Actin Filament Polymerization
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