IL18R1 anticorps (Extracellular Domain, N-Term)

N° du produit ABIN1449294

Détail du produit anti-IL18R1 anticorps

Antigène: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Épitope: AA 1-329, Extracellular Domain, N-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL18R1 est non-conjugé

Application: Flow Cytometry (FACS)

Specificité: This antibody detects IL-18R1.

Réactivité croisée (Details): Species reactivity (tested):Human (KG-1). Does not react with Mouse transfected cells.

Purification: Protein A agarose

Immunogène: Human IL-18R1 extracellular domain corresponding to amino acids 1-329

Clone: 44G6

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur IL18R1

Antigène: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Autre désignation: CD218a / IL18R1 (IL18R1 Produits)

Synonymes: anticorps CD218a, anticorps CDw218a, anticorps IL-1Rrp, anticorps IL18RA, anticorps IL1RRP, anticorps IL-1R9, anticorps IL1R9, anticorps IL1RAPL-2, anticorps TIGIRR-1, anticorps Il18ralpha, anticorps Il1rrp, anticorps IL-18Ra, anticorps IL18R1, anticorps interleukin 18 receptor 1, anticorps interleukin 1 receptor accessory protein like 2, anticorps IL18R1, anticorps IL1RAPL2, anticorps Il18r1

Sujet: IL-18 is a proinflammatory cytokine that can synergize with IL-12 to increase IFN-γ production, NK cell cytotoxity, and Th1 responses, and involves in chronic inflammation, autoimmune diseases, and a variety of cancers. The receptor of IL-18 is a complex of two polypeptide chains, IL-18 receptor 1 (IL-18R1/IL-18Ra/CD218a) and IL-18 receptor accessory protein (IL-18Rap/IL-18 receptor ß/CD218b). Both chain are essential for IL-18 signal transduction. IL-18R1 is a glycosylated membrane protein of 60-100 kDa expressed on variety of cells containing Th1 cells, NK cells, renal epithelial cells and prostate cancer cells. It is a member of IL-1 receptor family and works as ligand binding chain of IL-18R complex.Synonyms: CD218 antigen-like family member A, CDw218a, IL-18 receptor 1, IL-1Rrp, IL1 receptor-related protein, IL1RRP, Interleukin-18 receptor 1

ID gène: 8809

NCBI Accession: NP_003846

UniProt: Q13478