ANKLE2 anticorps (Middle Region)

N° du produit ABIN1449856

Détail du produit anti-ANKLE2 anticorps

Antigène: ANKLE2 (Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANKLE2 est non-conjugé

Application: Western Blotting (WB)

Séquence: CYSPSDRQSW PSPAVKGRFK SQLPDLSGPH SYSPGRNSVA GSNPAKPGLG

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogène: Synthetic peptide directed towards the middle region of human KIAA0692

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur ANKLE2

Antigène: ANKLE2 (Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2))

Autre désignation: ANKLE2 / KIAA0692 (ANKLE2 Produits)

Synonymes: anticorps KIAA0692, anticorps LEMD7, anticorps Lem4, anticorps 1110001J12Rik, anticorps AI661024, anticorps D5Ertd585e, anticorps RGD1310191, anticorps ankyrin repeat and LEM domain containing 2, anticorps ANKLE2, anticorps Ankle2

Sujet: ANKLE2 or KIAA0692 is a single-pass membrane protein. It contains 1 ANK repeat and 1 LEM domain. It contains 1 RING-type zinc finger. It is involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit. ANKLE2 coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex.Synonyms: Ankyrin repeat and LEM domain-containing protein 2

ID gène: 23141

NCBI Accession: NP_055929