AKAP5 anticorps (Middle Region)

N° du produit ABIN1449866

Détail du produit anti-AKAP5 anticorps

Antigène: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP5 est non-conjugé

Application: Western Blotting (WB)

Séquence: KQFLISAENE QVGVFANDNG FEDRTSEQYE TLLIETASSL VKNAIQLSIE

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Dog, BovineSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogène: Synthetic peptide directed towards the middle region of human AKAP5

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur AKAP5

Antigène: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Autre désignation: AKAP5 (AKAP5 Produits)

Synonymes: anticorps AKAP5, anticorps AKAP75, anticorps AKAP79, anticorps H21, anticorps AKAP, anticorps P75, anticorps 3526401B18Rik, anticorps AKAP 150, anticorps AKAP-5, anticorps AKAP150, anticorps BB098886, anticorps Gm258, anticorps P150, anticorps Akap79, anticorps A kinase (PRKA) anchor protein 5, anticorps A-kinase anchoring protein 5, anticorps AKAP5, anticorps Akap5

Classe de substances: Viral Protein

Sujet: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP5 is a member of the AKAP family. It binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.Synonyms: A-kinase anchor protein 5, A-kinase anchor protein 79 kDa, AKAP79, cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein

ID gène: 9495

NCBI Accession: NP_004848

Pathways: cAMP Metabolic Process