TMEM237 anticorps (Middle Region)

N° du produit ABIN1449912

Détail du produit anti-TMEM237 anticorps

Antigène: TMEM237 (Transmembrane Protein 237 (TMEM237))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM237 est non-conjugé

Application: Western Blotting (WB)

Séquence: AGDQLSNLSN LLQQYKTLAY PFQSLLYLLL ALSTISAFDR IDFAKISVAI

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogène: Synthetic peptide directed towards the middle region of human ALS2CR4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur TMEM237

Antigène: TMEM237 (Transmembrane Protein 237 (TMEM237))

Autre désignation: ALS2CR4 / TMEM237 (TMEM237 Produits)

Synonymes: anticorps ALS2CR4, anticorps JBTS14, anticorps Als2cr4, anticorps AI853305, anticorps Gm972, anticorps als2cr4, anticorps als2cr4a, anticorps si:dkey-33m14.6, anticorps als2cr4b, anticorps sb:cb992, anticorps zgc:101660, anticorps transmembrane protein 237, anticorps transmembrane protein 237a, anticorps transmembrane protein 237 L homeolog, anticorps transmembrane protein 237b, anticorps TMEM237, anticorps Tmem237, anticorps tmem237, anticorps tmem237a, anticorps tmem237.L, anticorps tmem237b

Sujet: TMEM237 or ALS2CR4 is a component of the transition zone in primary cilia and required for ciliogenesis. Defects in TMEM237 are the cause of Joubert syndrome type 14 (JBTS14). An autosomal recessive disorder characterized by severe mental retardation, hypotonia, breathing abnormalities in infancy, and dysmorphic facial features. Neuroradiologically, it is characterized by cerebellar vermian hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar tooth sign). Additional variable JBTS14 features include renal disease, abnormal eye movements, and postaxial polydactyly.Synonyms: Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein, Transmembrane protein 237

ID gène: 65062

NCBI Accession: NM_001044385