TSHZ3 anticorps (N-Term)

N° du produit ABIN1450132

Détail du produit anti-TSHZ3 anticorps

Antigène: TSHZ3 (ZNF537) (Zinc Finger Protein 537 (ZNF537))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSHZ3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid synthetic peptide near the amino terminus of human TSHZ3 / ZNF537

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TSHZ3

Antigène: TSHZ3 (ZNF537) (Zinc Finger Protein 537 (ZNF537))

Autre désignation: TSHZ3 / ZNF537 (ZNF537 Produits)

Synonymes: anticorps ZNF537, anticorps A630038G13Rik, anticorps Tsh3, anticorps Zfp537, anticorps mKIAA1474, anticorps teashirt3, anticorps TSH3, anticorps teashirt zinc finger homeobox 3, anticorps teashirt zinc finger family member 3, anticorps TSHZ3, anticorps Tshz3

Sujet: The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. In mice, the known three TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting that they play a role in the establishment of regional identity and specification of cell types within the brain. Both TSHZ3 and TSHZ1 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4. Recent experiments have also suggested this family of proteins may be involved in carcinogenesis.Synonyms: KIAA1474, TSH3, Teashirt homolog 3, Zinc finger protein 537

ID gène: 57616

NCBI Accession: NP_065907

Pathways: Regulation of Muscle Cell Differentiation