TRAF3 anticorps (AA 240-289)

N° du produit ABIN1454010

Cet anticorps anti-TRAF3 Polyclonal Lapin (ABIN1454010) détecte spécifiquement TRAF3 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour TRAF3 anticorps (AA 240-289) (ABIN1454010)

Antigène: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TRAF3 anticorps

Épitope: AA 240-289

Fonction: TRAF3 Antibody

Specificité: TRAF3 Polyclonal Antibody detects endogenous levels of TRAF3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human TRAF3. AA range:240-289

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TRAF3

Antigène: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Autre désignation: TRAF3

Sujet:

Synonyms: TRAF3, CAP1, CRAF1, TNF receptor-associated factor 3, CAP-1, CD40 receptor-associated factor 1, CRAF1, CD40-binding protein, CD40BP, LMP1-associated protein 1, LAP1

Background: TNF receptor associated factor 3(TRAF3) Homo sapiens The protein encoded byThis gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010],

Gene Name: TRAF3

Protein Name: TNF receptor-associated factor 3

Poids moléculaire: 64 kDa

ID gène: 7187

OMIM: 601896

UniProt: Q13114

Pathways: Signalisation NF-kappaB, Apoptose, Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades