BMP2 anticorps (AA 283-396)

N° du produit ABIN1512642

Détail du produit anti-BMP2 anticorps

Antigène: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Épitope: AA 283-396

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: QAKHKQRKRL KSSCKRHPLY VDFSDVGWND WIVAPPGYHA FYCHGECPFP LADHLNSTNH AIVQTLVNSV NSKIPKACCV PTELSAISML YLDENEKVVL KNYQDMVVEG CGCR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 283-396 of human BMP2 (NP_001191.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-BMP2 (ABIN1512642)

Wang, Zhou, Zhang, Shi, Xiao, Zeng, Yang, Zheng, Wang, Mai: "BMP2 promotes proliferation and invasion of nasopharyngeal carcinoma cells via mTORC1 pathway." dans: Aging, Vol. 9, Issue 4, pp. 1326-1340, (2018) (PubMed).

Détails sur BMP2

Antigène: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Autre désignation: BMP2 (BMP2 Produits)

Synonymes: anticorps BDA2, anticorps BMP2A, anticorps AI467020, anticorps Bmp2a, anticorps BMP-2, anticorps xBMP-2, anticorps xbmp2, anticorps BMP2, anticorps bmp2a, anticorps bmp2, anticorps wu:fc59d09, anticorps bone morphogenetic protein 2, anticorps bone morphogenetic protein 2 L homeolog, anticorps Bone morphogenetic protein 2, anticorps bone morphogenetic protein 2a, anticorps BMP2, anticorps Bmp2, anticorps bmp2.L, anticorps bmp2, anticorps bmp2a

Sujet: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.,BDA2,BMP2A,BMP2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,Growth factor,TGF-b-Smad Signaling Pathway,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Immunology & Inflammation,Cytokines,NF-kB Signaling Pathway,Stem Cells,Neural Stem Cells,Cardiovascular,Angiogenesis,Ligand,BMP2

Poids moléculaire: 44 kDa

ID gène: 650

UniProt: P12643

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation