EGFR anticorps (pSer1070)
Aperçu rapide pour EGFR anticorps (pSer1070) (ABIN1531818)
Antigène
Voir toutes EGFR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1041-1090, pSer1070
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Specificité
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EGFR (Phospho-Ser1070) Antibody detects endogenous levels of EGFR only when phosphorylated at Ser1070.
PhosphorylationH:S1070 M:S1070 R:S1069
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Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human EGFR around the phosphorylation site of Ser1070.
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Isotype
- IgG
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Indications d'application
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000
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Commentaires
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Unigene-Number: Hs.488293 (NCBI Gene Symbol: EGFR)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable at -20°C for at least 1 year.
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Date de péremption
- 12 months
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Autre désignation
- EGFR
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Sujet
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Synonyms: Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1 , EGFR , ERBB1
NCBI Gene Symbol: EGFR
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Poids moléculaire
- 134 kDa
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ID gène
- 1956
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OMIM
- 131550
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UniProt
- P00533
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Pathways
- Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
Antigène
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