EGFR anticorps (pTyr1197)

N° du produit ABIN1531822

Cet anticorps Lapin Polyclonal détecte spécifiquement EGFR dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour EGFR anticorps (pTyr1197) (ABIN1531822)

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EGFR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-EGFR anticorps

Épitope: AA 1161-1210, pTyr1197

Specificité:

EGFR (Phospho-Tyr1197) Antibody detects endogenous levels of EGFR only when phosphorylated at Tyr1197.

PhosphorylationH:Y1197 M:Y1197 R:Y1196

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human EGFR around the phosphorylation site of Tyr1197.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Commentaires:

Unigene-Number: Hs.488293 (NCBI Gene Symbol: EGFR)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable at -20°C for at least 1 year.

Date de péremption: 12 months

Détails sur EGFR

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Autre désignation: EGFR

Sujet:

Synonyms: Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1 , EGFR , ERBB1

NCBI Gene Symbol: EGFR

Poids moléculaire: 134 kDa

ID gène: 1956

OMIM: 131550

UniProt: P00533

Pathways: Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins