RHOA anticorps (AA 144-193)

N° du produit ABIN1532406

L’anticorps anti-RHOA Polyclonal Lapin est utilisé pour la détection de RHOA dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour RHOA anticorps (AA 144-193) (ABIN1532406)

Antigène: RHOA (Ras Homolog Gene Family, Member A (RHOA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHOA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-RHOA anticorps

Épitope: AA 144-193

Fonction: Rho A Antibody

Specificité: Rho A Polyclonal Antibody detects endogenous levels of Rho A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human RhoA. AA range:144-193

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur RHOA

Antigène: RHOA (Ras Homolog Gene Family, Member A (RHOA))

Autre désignation: RhoA

Sujet:

Synonyms: RHOA, ARH12, ARHA, RHO12, Transforming protein RhoA, Rho cDNA clone 12, h12

Background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015],

Gene Name: RHOA

Protein Name: Transforming protein RhoA

Poids moléculaire: 21 kDa

ID gène: 387

OMIM: 165390

UniProt: P61586

Pathways: Dynamique des Microtubules, Signalisation WNT, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome