GZMB anticorps (AA 10-59)

N° du produit ABIN1533296

Cet anticorps Lapin Polyclonal détecte spécifiquement GZMB dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GZMB anticorps (AA 10-59) (ABIN1533296)

Antigène: GZMB (Granzyme B (GZMB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GZMB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-GZMB anticorps

Épitope: AA 10-59

Fonction: Granzyme B/H Antibody

Specificité: Granzyme B/H Polyclonal Antibody detects endogenous levels of Granzyme B/H protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Granzyme B. AA range:10-59

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: Granzyme B

Sujet:

Synonyms: GZMB, CGL1, CSPB, CTLA1, GRB, Granzyme B, C11, CTLA-1, Cathepsin G-like 1, CTSGL1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, HLP, SECT, T-cell serine protease 1-3E, GZMH, C

Background: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016],

Gene Name: GZMB/GZMH

Protein Name: Granzyme B/H

Poids moléculaire: 27 kDa

ID gène: 2999

OMIM: 123910

UniProt: P10144

Pathways: Apoptose, Caspase Cascade in Apoptosis