TRADD anticorps (AA 251-300)

N° du produit ABIN1533447

Cet anticorps Lapin Polyclonal détecte spécifiquement TRADD dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Singe.

Aperçu rapide pour TRADD anticorps (AA 251-300) (ABIN1533447)

Antigène: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Reactivité: Humain, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRADD est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-TRADD anticorps

Épitope: AA 251-300

Fonction: TRADD Antibody

Specificité: TRADD Polyclonal Antibody detects endogenous levels of TRADD protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human TRADD. AA range:251-300

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TRADD

Antigène: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Autre désignation: TRADD

Sujet:

Synonyms: TRADD, Tumor necrosis factor receptor type 1-associated DEATH domain protein, TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain

Background: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008],

Gene Name: TRADD

Protein Name: Tumor necrosis factor receptor type 1-associated DEATH domain protein

Poids moléculaire: 34 kDa

ID gène: 8717

OMIM: 603500

UniProt: Q15628

Pathways: Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C