HMGB1 anticorps (AA 131-180)

N° du produit ABIN1533598

L’anticorps anti-HMGB1 Polyclonal Lapin est utilisé pour la détection de HMGB1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF, ICC, IHC (p) et IP.

Aperçu rapide pour HMGB1 anticorps (AA 131-180) (ABIN1533598)

Antigène: HMGB1 (High Mobility Group Box 1 (HMGB1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Détail du produit anti-HMGB1 anticorps

Épitope: AA 131-180

Fonction: HMG-1 Antibody

Specificité: HMG-1 Polyclonal Antibody detects endogenous levels of HMG-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human HMGB1. AA range:131-180

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur HMGB1

Antigène: HMGB1 (High Mobility Group Box 1 (HMGB1))

Autre désignation: HMGB1

Sujet:

Synonyms: HMGB1, HMG1, High mobility group protein B1, High mobility group protein 1, HMG-1

Background: thyroid peroxidase(TPO) Homo sapiens This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011],

Gene Name: HMGB1

Protein Name: High mobility group protein B1

Poids moléculaire: 24 kDa

OMIM: 163905

UniProt: P09429

Pathways: Signalisation p53, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome