RGS1 anticorps (AA 118-167)
Aperçu rapide pour RGS1 anticorps (AA 118-167) (ABIN1535285)
Antigène
Voir toutes RGS1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 118-167
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Fonction
- RGS1 Antibody
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Specificité
- RGS1 Polyclonal Antibody detects endogenous levels of RGS1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human RGS1. AA range:118-167
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- RGS1 (Regulator of G-Protein Signaling 1 (RGS1))
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Autre désignation
- RGS1
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Sujet
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Synonyms: RGS1, 1R20, BL34, IER1, Regulator of G-protein signaling 1, RGS1, B-cell activation protein BL34, Early response protein 1R20
Background: This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008],
Gene Name: RGS1
Protein Name: Regulator of G-protein signaling 1
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Poids moléculaire
- 22 kDa
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ID gène
- 5996
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OMIM
- 600323
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UniProt
- Q08116
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Pathways
- Signalisation MAPK, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events
Antigène
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