Actin anticorps

N° du produit ABIN1536597

Détail du produit anti-Actin anticorps

Antigène: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Actin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie: B, C, M, Pig, Rb, Rat

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This ACTA1 monoclonal antibody is generated from mouse immunized with ACTA1 recombinant protein.

Clone: 337CT30-10-1

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 1:500-1:1000. WB: 1:1000. IHC-P: 1:10~50. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: ACTA1 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Actin (ABIN1536597)

Vuković, Jevtić, Zhang, Stohr, Levy: "Nuclear size is sensitive to NTF2 protein levels in a manner dependent on Ran binding." dans: Journal of cell science, Vol. 129, Issue 6, pp. 1115-27, (2017) (PubMed).

Edens, Dilsaver, Levy: "PKC-mediated phosphorylation of nuclear lamins at a single serine residue regulates interphase nuclear size in Xenopus and mammalian cells." dans: Molecular biology of the cell, Vol. 28, Issue 10, pp. 1389-1399, (2017) (PubMed).

Détails sur Actin

Antigène: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Autre désignation: ACTA1 (ACTA1 Produits)

Synonymes: anticorps ACTA, anticorps ASMA, anticorps CFTD, anticorps CFTD1, anticorps CFTDM, anticorps MPFD, anticorps NEM1, anticorps NEM2, anticorps NEM3, anticorps acta, anticorps asma, anticorps cftd, anticorps cftd1, anticorps cftdm, anticorps mpfd, anticorps nem1, anticorps AA959943, anticorps Acta-2, anticorps Acts, anticorps Actsk-1, anticorps actc, anticorps actc1, anticorps cfk, anticorps hm:zeh0631, anticorps zeh0631, anticorps acta1, anticorps hm:zeh0293, anticorps zgc:112098, anticorps actin, alpha 1, skeletal muscle, anticorps actin, alpha 1, skeletal muscle L homeolog, anticorps actin, alpha 1b, skeletal muscle, anticorps actin, muscle, anticorps actin, alpha skeletal muscle, anticorps actin, alpha 1a, skeletal muscle, anticorps ACTA1, anticorps acta1.L, anticorps acta1, anticorps Acta1, anticorps acta1b, anticorps LOC100533357, anticorps LOC109479779, anticorps LOC109108280, anticorps acta1a

Sujet: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Poids moléculaire: 42051

ID gène: 58

NCBI Accession: NP_001091

UniProt: P68133

Pathways: Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development