NOTCH3 anticorps (C-Term)
Aperçu rapide pour NOTCH3 anticorps (C-Term) (ABIN1537680)
Antigène
Voir toutes NOTCH3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 2291-2321, C-Term
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Purification
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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Immunogène
- This NOTCH3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 2291-2321 amino acids from the C-terminal region of human NOTCH3.
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Isotype
- IgG1
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Indications d'application
- WB: 1:2000. WB: 1:100~250
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- NOTCH3 Antibody (C-term Q2306) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Date de péremption
- 6 months
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- NOTCH3 (Notch 3 (NOTCH3))
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Autre désignation
- NOTCH3
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Sujet
- This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq].
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Poids moléculaire
- 243631
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ID gène
- 4854
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NCBI Accession
- NP_000426
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UniProt
- Q9UM47
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Pathways
- Signalisation Notch
Antigène
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