This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This ABCC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-669 amino acids from the Central region of human ABCC9.
anticorps SUR2B, anticorps DDBDRAFT_0215814, anticorps DDBDRAFT_0216237, anticorps DDB_0215814, anticorps DDB_0216237, anticorps si:dkey-183c2.3, anticorps sur2, anticorps ABC37, anticorps ATFB12, anticorps CANTU, anticorps CMD1O, anticorps SUR2, anticorps SUR2A, anticorps AI414027, anticorps AI449286, anticorps Sur2, anticorps ABCC9, anticorps ATP binding cassette subfamily C member 9, anticorps ATP-binding cassette sub-family C member 8, anticorps ABC transporter C family protein, anticorps ATP-binding cassette sub-family C member 9, anticorps ATP-binding cassette, sub-family C (CFTR/MRP), member 9, anticorps ABCC9, anticorps LOC581821, anticorps abcC9, anticorps LOC100470981, anticorps abcc9, anticorps Abcc9
Sujet
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has been associated with this gene thus far. Alternative splicing of this gene results in several products, two of which result from differential usage of two terminal exons and one of which results from exon deletion.