DROSHA anticorps (AA 737-764)

N° du produit ABIN1538601

Détail du produit anti-DROSHA anticorps

Antigène: DROSHA (Drosha, Ribonuclease Type III (DROSHA))

Épitope: AA 737-764

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DROSHA est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse Rnasen antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 737-764 amino acids from the Central region of mouse Rnasen.

Clone: RB38658

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Mouse Rnasen Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur DROSHA

Antigène: DROSHA (Drosha, Ribonuclease Type III (DROSHA))

Autre désignation: Rnasen (DROSHA Produits)

Synonymes: anticorps im:7150667, anticorps zgc:158612, anticorps ETOHI2, anticorps HSA242976, anticorps RANSE3L, anticorps RN3, anticorps RNASE3L, anticorps RNASEN, anticorps 1110013A17Rik, anticorps AI874853, anticorps Etohi2, anticorps Rn3, anticorps Rnasen, anticorps RGD1307626, anticorps ribonuclease type III, nuclear, anticorps Ribonuclease 3, anticorps ribonuclease 3, anticorps drosha ribonuclease III, anticorps drosha, ribonuclease type III, anticorps rnasen, anticorps Thicy_0885, anticorps Sinme_0866, anticorps Isova_2087, anticorps Sphch_0770, anticorps DROSHA, anticorps Drosha

Sujet: Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, RNASEN/DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies (By similarity).

Poids moléculaire: 158828

ID gène: 14000

NCBI Accession: NP_001123621, NP_081075

UniProt: Q5HZJ0

Pathways: Regulatory RNA Pathways