DROSHA anticorps (C-Term)

N° du produit ABIN6971610

Détail du produit anti-DROSHA anticorps

Antigène: DROSHA (Drosha, Ribonuclease Type III (DROSHA))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DROSHA est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Attributs du produit: Drosha is an RNAse III enzyme that is involved in the process of generating microRNA (miRNA). miRNA interacts with the RNA-induced silencing complex (RISC) to cleave mRNA and thus downregulate gene expression. Drosha is a double stranded RNAse and part of the Microprocessor complex. Other RNAse III enzymes include Dicer and Argonaute. Drosha initiates processing of the miRNA precursor (pri-miRNA) in the nucleus, which is then exported to the cytoplasm and further cleaved by Dicer into a mature miRNA. Drosha antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogène: This Drosha antibody was raised against a peptide within the C-terminal region of human Drosha.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur DROSHA

Antigène: DROSHA (Drosha, Ribonuclease Type III (DROSHA))

Autre désignation: Drosha (DROSHA Produits)

Synonymes: anticorps im:7150667, anticorps zgc:158612, anticorps ETOHI2, anticorps HSA242976, anticorps RANSE3L, anticorps RN3, anticorps RNASE3L, anticorps RNASEN, anticorps 1110013A17Rik, anticorps AI874853, anticorps Etohi2, anticorps Rn3, anticorps Rnasen, anticorps RGD1307626, anticorps ribonuclease type III, nuclear, anticorps Ribonuclease 3, anticorps ribonuclease 3, anticorps drosha ribonuclease III, anticorps drosha, ribonuclease type III, anticorps rnasen, anticorps Thicy_0885, anticorps Sinme_0866, anticorps Isova_2087, anticorps Sphch_0770, anticorps DROSHA, anticorps Drosha

Poids moléculaire: 160 kDa

NCBI Accession: NP_037367

Pathways: Regulatory RNA Pathways