PARP1 anticorps (pSer372)
Aperçu rapide pour PARP1 anticorps (pSer372) (ABIN1539703)
Antigène
Voir toutes PARP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- pSer372
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This PARP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S372 of human PARP1.
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Isotype
- Ig Fraction
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Indications d'application
- DB: 1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Phospho-PARP1-S372 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Date de péremption
- 6 months
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- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
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Autre désignation
- PARP1
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Sujet
- This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
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Poids moléculaire
- 113084
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ID gène
- 142
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NCBI Accession
- NP_001609
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UniProt
- P09874
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Réparation de l'ADN, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
Antigène
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