FCGR3A anticorps (AA 60-88)

N° du produit ABIN1539896

Détail du produit anti-FCGR3A anticorps

Antigène: FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))

Épitope: AA 60-88

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FCGR3A est non-conjugé

Application: Western Blotting (WB)

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogène: This FCGR3A antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from human FCGR3A.

Clone: 441CT4-2-1

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:100~400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: FCGR3A Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur FCGR3A

Antigène: FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))

Autre désignation: FCGR3A (FCGR3A Produits)

Synonymes: anticorps CD16, anticorps CD16A, anticorps FCG3, anticorps FCGR3, anticorps FCGRIII, anticorps FCR-10, anticorps FCRIII, anticorps FCRIIIA, anticorps IGFR3, anticorps Fcgr4, anticorps Fc fragment of IgG receptor IIIa, anticorps FCGR3A, anticorps Fcgr3a

Sujet: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 29089

ID gène: 2214

NCBI Accession: NP_000560, NP_001121064, NP_001121065, NP_001121067, NP_001121068

UniProt: P08637