RYBP anticorps
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- Antigène Voir toutes RYBP Anticorps
- RYBP (RING1 and YY1 Binding Protein (RYBP))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RYBP est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects DEDAF. A 32 kDa band should be detected.
- Purification
- Affinity purified
- Immunogène
- Synthetic peptide surrounding amino acid 218 of human DEDAF.
- Top Product
- Discover our top product RYBP Anticorps primaire
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- Indications d'application
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Western Blot: 0.5-4 μg/mL. A549 or HepG2 cell lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C/-80 °C
- Stockage commentaire
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- Antigène
- RYBP (RING1 and YY1 Binding Protein (RYBP))
- Autre désignation
- RYBP (RYBP Produits)
- Synonymes
- anticorps AAP1, anticorps DEDAF, anticorps YEAF1, anticorps 2410018J24Rik, anticorps rybp, anticorps aap1, anticorps dedaf, anticorps yeaf1, anticorps cb337, anticorps wu:fi34f03, anticorps Dedaf, anticorps zgc:153842, anticorps RING1 and YY1 binding protein, anticorps RING1 and YY1 binding protein L homeolog, anticorps RING1 and YY1 binding protein a, anticorps RING1 and YY1 binding protein b, anticorps RYBP, anticorps Rybp, anticorps rybp, anticorps rybp.L, anticorps rybpa, anticorps rybpb
- Sujet
- Cell death signal are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. A novel protein that interacts with DED of caspase-8 and -10, and FADD was recently identified and designated DEDAF (for DED associated factor). DEDAF is identical to the transcriptional repressor RYBP. DEDAF interacts with FADD and augments the formation of CD95/FADD/caspase-8 complexes at the cytoplasm. DEDAF also interacts with DED-containing DNA biding protein (DEDD) in the nucleus, indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis.Synonyms: AAP-1, APAP-1, Apoptin-associating protein 1, DED-associated factor, DEDAF, Death effector domain-associated factor, RING1 and YY1-binding protein, YEAF1, YY1 and E4TF1-associated factor 1
- ID gène
- 23429
- NCBI Accession
- NP_036366
- UniProt
- Q8N488
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