RYBP anticorps

N° du produit ABIN155069

L’anticorps anti-RYBP Polyclonal Lapin est utilisé pour la détection de RYBP dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour RYBP anticorps (ABIN155069)

Antigène: RYBP (RING1 and YY1 Binding Protein (RYBP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RYBP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RYBP anticorps

Specificité: This antibody detects DEDAF. A 32 kDa band should be detected.

Purification: Affinity purified

Immunogène: Synthetic peptide surrounding amino acid 218 of human DEDAF.

Information d'application

Indications d'application: Western Blot: 0.5-4 μg/mL. A549 or HepG2 cell lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur RYBP

Antigène: RYBP (RING1 and YY1 Binding Protein (RYBP))

Autre désignation: RYBP

Sujet: Cell death signal are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. A novel protein that interacts with DED of caspase-8 and -10, and FADD was recently identified and designated DEDAF (for DED associated factor). DEDAF is identical to the transcriptional repressor RYBP. DEDAF interacts with FADD and augments the formation of CD95/FADD/caspase-8 complexes at the cytoplasm. DEDAF also interacts with DED-containing DNA biding protein (DEDD) in the nucleus, indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis.Synonyms: AAP-1, APAP-1, Apoptin-associating protein 1, DED-associated factor, DEDAF, Death effector domain-associated factor, RING1 and YY1-binding protein, YEAF1, YY1 and E4TF1-associated factor 1

ID gène: 23429

NCBI Accession: NP_036366

UniProt: Q8N488