SPI1 anticorps (C-Term)
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- Antigène Voir toutes SPI1 Anticorps
- SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SPI1 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- PU.1 Antibody, pAb, Rabbit detects human PU.1 protein.
- Purification
- Immunoaffinity chromatography
- Immunogène
- KLH-coupled synthetic peptide from C-terminal of human PU.1
- Isotype
- IgG1
- Top Product
- Discover our top product SPI1 Anticorps primaire
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- Indications d'application
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Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western Blot: 1-2 µg/mLOther Applications: user optimized - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4, containing 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
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- Antigène
- SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
- Autre désignation
- PU.1 (SPI1 Produits)
- Synonymes
- anticorps OF, anticorps PU.1, anticorps SFPI1, anticorps SPI-1, anticorps SPI-A, anticorps Dis-1, anticorps Dis1, anticorps Sfpi-1, anticorps Sfpi1, anticorps Spi-1, anticorps Tcfpu1, anticorps Tfpu.1, anticorps Pu.1, anticorps cb1086, anticorps pu.1, anticorps pu1, anticorps sfpi1, anticorps si:by184l24.2, anticorps spi1, anticorps SPI1/PU.1, anticorps spi1l, anticorps zgc:152991, anticorps Spi-1 proto-oncogene, anticorps spleen focus forming virus (SFFV) proviral integration oncogene, anticorps Spi-1 proto-oncogene b, anticorps Spi-1 proto-oncogene a, anticorps SPI1, anticorps Spi1, anticorps spi1b, anticorps spi1a
- Sujet
- PU.1 known as Spi1 and Sfpi1, is an ETS-domain transcription factor essential for the development of myeloid and B-lymphoid cells. In myeloid cells, PU.1 may regulate transcription of both FMS and CD18/11B proteins that are central to the osteoclast phenotype. The failure to express PU.1 might preclude development of osteoclasts, leading to arrested bone resorption and osteopetrosis. PU.1 expression increases with the induction of osteoclastogenesis by either 1,25-dihydroxyvitamin D3 or dexamethasone which confirms the association between PU.1 and osteoclast differentiation. PU.1 Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human PU.1 protein (Swiss Prot: P17947).
- Pathways
- Stem Cell Maintenance
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