FAM193B anticorps (N-Term)
-
- Antigène Tous les produits FAM193B
- FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))
-
Épitope
- N-Term
- Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp FAM193B est non-conjugé
-
Application
- Western Blotting (WB), Immunofluorescence (IF), ELISA
- Specificité
- At least two isoforms of FAM193B are known to exist, this antibody will detect both isoforms.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- FAM193B antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human FAM193B.
- Isotype
- IgG
-
-
- Indications d'application
- FAM193B antibody can be used for detection of FAM193B by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
- Commentaires
-
(NT) Family with sequence similarity 193 member B
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Stock
- 4 °C
- Stockage commentaire
- FAM193B antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Date de péremption
- 12 months
-
- Antigène
- FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))
- Autre désignation
- FAM193B (FAM193B Produits)
- Synonymes
- anticorps IRIZIO, anticorps Kiaa1931, anticorps family with sequence similarity 193 member B, anticorps family with sequence similarity 193, member B, anticorps FAM193B, anticorps Fam193b
- Sujet
- FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.
- Poids moléculaire
- 99 kDa
- ID gène
- 54540
- UniProt
- Q96PV7
-