LGALS1/Galectin 1 anticorps
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- Antigène Voir toutes LGALS1/Galectin 1 (LGALS1) Anticorps
- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LGALS1/Galectin 1 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- Recombinant human Galectin-1
- Attributs du produit
- Chromosomal location: 22q13.1
- Isotype
- IgG
- Top Product
- Discover our top product LGALS1 Anticorps primaire
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- Indications d'application
- Western Blot: use 1-5 µg/mL
- Commentaires
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Rabbit IG Polyclonal Antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- 3 mM PBS, pH 7.2
- Conseil sur la manipulation
- Centrifuge vial prior to opening.
- Stock
- -20 °C
- Stockage commentaire
- The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
- Autre désignation
- Galectin-1 (LGALS1 Produits)
- Synonymes
- anticorps GAL1, anticorps GBP, anticorps Galectin-1, anticorps LGAS1, anticorps LGALS1, anticorps MGC64502, anticorps GB10026, anticorps AA410090, anticorps Gal-1, anticorps Galbp, anticorps L-14.5, anticorps L14, anticorps Lect14, anticorps galectin-1, anticorps Galaptin, anticorps galectin 1, anticorps galectin-1, anticorps lectin, galactoside-binding, soluble, 1 L homeolog, anticorps protein enabled, anticorps lectin, galactose binding, soluble 1, anticorps LGALS1, anticorps Lgals1, anticorps CC1G_05003, anticorps CC1G_05004, anticorps lgals1.L, anticorps LOC408848
- Sujet
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Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine production. Galectin1 can also modulate cel-lcell as well as cell-lmatrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and antiinflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity. Human and mouse galectin1 share about 88% amino acid sequence similarity.
Synonyms: LGALS1, GBP, GAL1 - NCBI Accession
- NM_002305, NP_002296
- UniProt
- P09382
- Pathways
- Carbohydrate Homeostasis
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