BCL3 anticorps (FITC)

N° du produit ABIN161382

Détail du produit anti-BCL3 anticorps (FITC)

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp BCL3 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Specificité: Mouse Bcl-3

Purification: Purified from ascites via Protein G Chromatography

Immunogène: recombinant Bcl-3-6-histidine tag . Fusion Partner: SP2/0 myeloma . Donor: Armenian Hamster

Clone: Ham 150-3-5

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: 0.1 mg/ml

Buffer: FITC conjugated Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur BCL3

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Autre désignation: Bcl-3 (BCL3 Produits)

Synonymes: anticorps BCL3, anticorps AI528691, anticorps Bcl-3, anticorps BCL4, anticorps D19S37, anticorps B-cell CLL/lymphoma 3, anticorps B cell leukemia/lymphoma 3, anticorps BCL3, anticorps Bcl3

Sujet: Anti-mouse Bcl-3 monoclonal antibody reacts with both mouse and human Bcl-3 (B-cell Leukemia/lymphoma 3). The proto-oncoprotein Bcl-3 is a member of the IkappaB family and is present predominantly in the nucleus. This protein has been shown to function as a transcriptional co-activator for homodimers of NF-kappaB p50 and p50B. In addition to p50 and p52, Bcl-3 also associates with nuclear proteins Jab1, Pirin, Tip60 and Bard1. The mouse Bcl-3 coding region exhibits 80% homology with human Bcl-3 which is associated with human B-cell chronic lymphocytic leukemias (CLLs). Bcl-3 is detected in various tissues such as spleen and other lymphoid organs. Applications for this clone include Western blotting, ELISA and flow cytometry.

Pathways: Signalisation NF-kappaB, Maintenance of Protein Location, Protein targeting to Nucleus