COMT anticorps (AA 42-221)

N° du produit ABIN1679321

Détail du produit anti-COMT anticorps

Antigène: COMT (Catechol-O-Methyltransferase (COMT))

Épitope: AA 42-221

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COMT est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Séquence: VGDKKGKIVD AVIQEHQPSV LLELGAYCGY SAVRMARLLS PGARLITIEI NPDCAAITQR MVDFAGVKDK VTLVVGASQD IIPQLKKKYD VDTLDMVFLD HWKDRYLPDT LLLEECGLLR KGTVLLADNV ICPGAPDFLA HVRGSSCFEC THYQSFLEYR EVVDGLEKAI YKGPGSEAGP

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 42-221 of human COMT (NP_009294.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IP,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur COMT

Antigène: COMT (Catechol-O-Methyltransferase (COMT))

Autre désignation: COMT (COMT Produits)

Synonymes: anticorps Comt1, anticorps D16Wsu103e, anticorps D330014B15Rik, anticorps COMT, anticorps mb-comt, anticorps s-comt, anticorps comt, anticorps MGC154444, anticorps zgc:114157, anticorps si:dkey-13a21.15, anticorps zK13A21.15, anticorps zgc:162236, anticorps catechol-O-methyltransferase, anticorps microRNA 4761, anticorps catechol-O-methyltransferase S homeolog, anticorps methyltransferase, anticorps catechol-o-methyltransferase, anticorps catechol-O-methyltransferase a, anticorps catechol-O-methyltransferase b, anticorps catechol O-methyltransferase, anticorps COMT, anticorps Comt, anticorps MIR4761, anticorps comt, anticorps comt.2, anticorps comt.S, anticorps Rv1703c, anticorps Mb1729c, anticorps comta, anticorps comtb, anticorps LOC100354142

Sujet: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.,COMT,HEL-S-98n,Epigenetics & Nuclear Signaling,Signal Transduction,Endocrine & Metabolism,Drug metabolism,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,COMT

Poids moléculaire: 24 kDa/30 kDa

ID gène: 1312

UniProt: P21964

Pathways: Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome