UQCRC1 anticorps (AA 156-480)

N° du produit ABIN1683221

Détail du produit anti-UQCRC1 anticorps

Antigène: UQCRC1 (Ubiquinol-Cytochrome C Reductase Core Protein I (UQCRC1))

Épitope: AA 156-480

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UQCRC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LEDSQIEKER DVILREMQEN DASMRDVVFN YLHATAFQGT PLAQAVEGPS ENVRKLSRAD LTEYLSTHYK APRMVLAAAG GVEHQQLLDL AQKHLGGIPW TYAEDAVPTL TPCRFTGSEI RHRDDALPFA HVAIAVEGPG WASPDNVALQ VANAIIGHYD CTYGGGVHLS SPLASGAVAN KLCQSFQTFS ICYAETGLLG AHFVCDRMKI DDMMFVLQGQ WMRLCTSATE SEVARGKNIL RNALVSHLDG TTPVCEDIGR SLLTYGRRIP LAEWESRIAE VDASVVREIC SKYIYDQCPA VAGYGPIEQL PDYNRIRSGM FWLRF

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 156-480 of human UQCRC1 (NP_003356.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur UQCRC1

Antigène: UQCRC1 (Ubiquinol-Cytochrome C Reductase Core Protein I (UQCRC1))

Autre désignation: UQCRC1 (UQCRC1 Produits)

Synonymes: anticorps MGC53748, anticorps zgc:73404, anticorps zgc:85750, anticorps 1110032G10Rik, anticorps D3S3191, anticorps QCR1, anticorps UQCR1, anticorps ubiquinol-cytochrome c reductase core protein 1 L homeolog, anticorps ubiquinol-cytochrome c reductase core protein 1, anticorps ubiquinol-cytochrome c reductase core protein I, anticorps cytochrome b-c1 complex subunit 1, mitochondrial, anticorps uqcrc1.L, anticorps uqcrc1, anticorps UQCRC1, anticorps LOC100020379, anticorps LOC100074417, anticorps LOC100347571, anticorps LOC100413740, anticorps LOC100452425, anticorps Uqcrc1

Sujet: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII, ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII and cytochrome c oxidase (complex IV, CIV, that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c (By similarity. The 2 core subunits UQCRC1/QCR1 and UQCRC2/QCR2 are homologous to the 2 mitochondrial-processing peptidase (MPP subunits beta-MPP and alpha-MPP respectively, and they seem to have preserved their MPP processing properties (By similarity. May be involved in the in situ processing of UQCRFS1 into the mature Rieske protein and its mitochondrial targeting sequence (MTS/subunit 9 when incorporated into complex III (Probable.,UQCRC1,D3S3191,QCR1,UQCR1,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,UQCRC1

Poids moléculaire: 52 kDa

ID gène: 7384

UniProt: P31930