AGO4 anticorps (AA 401-500) (Alexa Fluor 488)

N° du produit ABIN1695156

Détail du produit anti-AGO4 anticorps (Alexa Fluor 488)

Antigène: AGO4 (EIF2C4) (Eukaryotic Translation Initiation Factor 2C, 4 (EIF2C4))

Épitope: AA 401-500

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGO4 est conjugé à/à la Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Argonaute 4/eIF2C4

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur AGO4

Antigène: AGO4 (EIF2C4) (Eukaryotic Translation Initiation Factor 2C, 4 (EIF2C4))

Autre désignation: Argonaute 4/e2C4 (EIF2C4 Produits)

Synonymes: anticorps EIF2C4, anticorps ago4, anticorps Argonaute4, anticorps argonaute-4, anticorps eif2c4, anticorps wu:fd14f04, anticorps ARGONAUTE 4, anticorps OCP11, anticorps OVEREXPRESSOR OF CATIONIC PEROXIDASE 11, anticorps T20P8.9, anticorps T20P8_9, anticorps Eif2c4, anticorps 5730550L01Rik, anticorps AI481660, anticorps argonaute 4, RISC catalytic component, anticorps argonaute 1, RISC catalytic component, anticorps argonaute RISC catalytic component 4, anticorps Argonaute family protein, anticorps argonaute 4, RISC catalytic component L homeolog, anticorps argonaute RISC catalytic subunit 4, anticorps AGO4, anticorps ago1, anticorps ago4, anticorps Ago4, anticorps ago4.L

Sujet:

Synonyms: 5730550L01Rik, Ago 4, Ago4, AGO4_HUMAN, Argonaute4, E 2C 4, e-2C 4, e2C 4, E2c4, eukaryotic translation initiation factor 2C 4, eukaryotic translation initiation factor 2C, hAgo4, KIAA1567, Piwi/Argonaute family protein me2C4, Protein argonaute-4.

Background: Eukaryotic translation initiation factor 2C (eIF2C) proteins (argonaute family) influence RNA interference (RNAi) as components of the RNA-inducible silencing complex (RISC) or microRNA (miRNA)-containing ribonucleoprotein particle (miRNP). Small RNAs, including small interfering RNAs (siRNAs) and miRNAs, can silence target genes through mechanisms that utilize RISC or miRNP particles. eIF2C1 (argonaute 1, AGO1, eIF2C, GERP95, Q99) and Dicer1 play a coordinated role in siRNA-mediated gene silencing. eIF2C2 (Slicer, argonaute 2, AGO2, Q10) is a RISC component that can concentrate in cytoplasmic processing bodies (P-bodies) and catalyze mRNA cleavage. Mammalian P-bodies contain mRNAs and have an association with miRNA-induced translational silencing and siRNA-induced mRNA degradation. Additional eIF2C proteins include eIF2C3 (argonaute 3, AGO3), eIF2C4 (argonaute 4, AGO4) and meIF2c5 (mouse argonaute 5).

ID gène: 192670

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process