FAM20C anticorps (AA 351-450) (Alexa Fluor 647)

N° du produit ABIN1698736

Détail du produit anti-FAM20C anticorps (Alexa Fluor 647)

Antigène: FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))

Épitope: AA 351-450

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM20C est conjugé à/à la Alexa Fluor 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Horse,Chicken,Monkey

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FAM20C

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FAM20C

Antigène: FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))

Autre désignation: FAM20C (FAM20C Produits)

Synonymes: anticorps DMP-4, anticorps DMP4, anticorps GEF-CK, anticorps RNS, anticorps C76981, anticorps mKIAA4081, anticorps RGD1311980, anticorps si:ch73-266a4.1, anticorps FAM20C, golgi associated secretory pathway kinase, anticorps family with sequence similarity 20, member C, anticorps family with sequence similarity 20, member Cb, anticorps FAM20C, anticorps Fam20c, anticorps fam20cb

Sujet:

Synonyms: C76981, Dentin matrix protein 4, DKFZp547C074, DMP-4, DMP4, DMP4_HUMAN, Extracellular serine/threonine protein kinase Fam20C, Fam20C, Family with sequence similarity 20 member C, GEF CK, Golgi enriched fraction casein kinase, Protein FAM20C, RNS antibod.

Background: The FAM20 proteins are a family of secreted proteins that regulate differentiation and function of hematopoietic and other tissues. FAM20C, also known as DMP4 (Dentin matrix protein 4), is a 570 amino acid secreted protein that binds calcium and may play a role in dentin mineralization. Defects in the gene encoding FAM20C are the cause of Raine syndrome (Lethal osteosclerotic bone dysplasia), an autosomal recessive osteosclerotic bone dysplasia, that is characterized by generalized osteosclerosis, microencephaly and craniofacial dysplasia. Usually, affected individuals survive only days or weeks. The mutations of the FAM20C gene include four nonsynomous base changes and four splice-site changes that have a detrimental affect on splicing.

ID gène: 56975

UniProt: Q8IXL6