Lethal (2) I16 (L(2)I16) (AA 701-785) anticorps (Biotin)

N° du produit ABIN1700040

Détail du produit

Antigène: Lethal (2) I16 (L(2)I16)

Épitope: AA 701-785

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IFI16

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Lethal (2) I16 (L(2)I16)

Autre désignation: I16

Sujet:

Synonyms: I16, Gamma interferon inducible protein 16, Gamma-interferon-inducible protein i16, IF16_HUMAN, i204, NGIP1, interferon activated gene 204, Interferon gamma induced protein I 16, Interferon gamma inducible protein 16, Interferon-inducible myeloid dferentiation transcriptional activator, p204, PYHIN2.

Background: IFI16 is a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

ID gène: 3428

UniProt: Q16666