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DRAXIN anticorps (AA 251-349) (Biotin)

DRAXIN Reactivité: Humain WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1700792
  • Antigène Voir toutes DRAXIN Anticorps
    DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))
    Épitope
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 251-349
    Reactivité
    • 37
    • 22
    • 21
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 36
    • 3
    Lapin
    Clonalité
    • 39
    Polyclonal
    Conjugué
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp DRAXIN est conjugé à/à la Biotin
    Application
    • 39
    • 26
    • 13
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human C1orf187
    Isotype
    IgG
    Top Product
    Discover our top product DRAXIN Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))
    Autre désignation
    C1orf187 (DRAXIN Produits)
    Synonymes
    anticorps C1orf187, anticorps draxin, anticorps AGPA3119, anticorps UNQ3119, anticorps neucrin, anticorps 2610109H07Rik, anticorps MGC113312, anticorps dorsal inhibitory axon guidance protein, anticorps DRAXIN, anticorps Draxin, anticorps draxin
    Sujet

    Synonyms: AGPA3119, C1orf187, Chromosome 1 open reading frame 187, Dorsal inhibitory axon guidance protein, Dorsal repulsive axon guidance protein, DRAXI_HUMAN, Draxin, FLJ34999, MGC117222, Neucrin, OTTHUMP00000002262, UNQ3119.

    Background: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic _-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.

    ID gène
    374946
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