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Allergin-1 anticorps (AA 61-160) (Cy5.5)

MILR1 Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5.5
N° du produit ABIN1705632
  • Antigène Voir toutes Allergin-1 (MILR1) Anticorps
    Allergin-1 (MILR1) (Mast Cell Immunoglobulin-Like Receptor 1 (MILR1))
    Épitope
    • 14
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 61-160
    Reactivité
    • 25
    • 3
    Humain
    Hôte
    • 22
    • 4
    • 1
    Lapin
    Clonalité
    • 23
    • 4
    Polyclonal
    Conjugué
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Allergin-1 est conjugé à/à la Cy5.5
    Application
    • 12
    • 12
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Allergin-1
    Isotype
    IgG
    Top Product
    Discover our top product MILR1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Allergin-1 (MILR1) (Mast Cell Immunoglobulin-Like Receptor 1 (MILR1))
    Autre désignation
    Allergin-1 (MILR1 Produits)
    Synonymes
    anticorps Allergin-1, anticorps Gm885, anticorps Mca32, anticorps C17orf60, anticorps MCA-32, anticorps MCA32, anticorps mast cell immunoglobulin like receptor 1, anticorps mast cell immunoglobulin-like receptor 1, anticorps Milr1, anticorps MILR1
    Sujet

    Synonyms: C17orf60,Chromosome 17 open reading frame 60.

    Background: As a major event in type allergic reaction,degranulation of mast cells is triggered by the interaction between specific IgEs and high affinity IgE receptors (FcRIs) on mast cell membrane,and is followed by the release of a battery of inflammatory mediators,such as histamine,leukotrienes and arachidonic acid,and these inflammatory mediators in turn induce a series of allergic symptoms.Recently,Allergin-1 has been found to be an immunoglobulin-like receptor preferentially expressed on mast cells.The crosslinking of Allergin-1 to FcRIs on mast cells may inhibit the signal transduction from FcRIs to intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM),generate ITIM inhibitory signals,which then participate in the regulation of mast cell degranulation,and finally block the initiation of allergic inflammation.

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