CD3 epsilon anticorps (AA 11-100) (FITC)
Aperçu rapide pour CD3 epsilon anticorps (AA 11-100) (FITC) (ABIN1710834)
Antigène
Voir toutes CD3 epsilon (CD3E) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 11-100
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Réactivité croisée
- Humain, Souris, Porc
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from pig CD3E
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Isotype
- IgG
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Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- CD3 epsilon (CD3E)
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Autre désignation
- CD3E
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Sujet
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Synonyms: CD3, T-cell surface glycoprotein CD3 epsilon chain, CD3e
Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].
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ID gène
- 397455
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UniProt
- Q7YRN2
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Pathways
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
Antigène
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