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TMEM245 anticorps (AA 201-300) (HRP)

TMEM245 Reactivité: Humain IHC (p), IHC (fro), WB Hôte: Lapin Polyclonal HRP
N° du produit ABIN1711160
  • Antigène Tous les produits TMEM245
    TMEM245 (Transmembrane Protein 245 (TMEM245))
    Épitope
    AA 201-300
    Reactivité
    Humain
    Hôte
    • 14
    Lapin
    Clonalité
    • 14
    Polyclonal
    Conjugué
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TMEM245 est conjugé à/à la HRP
    Application
    • 13
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
    Homologie
    Human,Dog,Cow,Sheep
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human C9orf5
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C/-80 °C
    Stockage commentaire
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Date de péremption
    12 months
  • Antigène
    TMEM245 (Transmembrane Protein 245 (TMEM245))
    Autre désignation
    C9orf5 (TMEM245 Produits)
    Synonymes
    anticorps C9orf5, anticorps CG-2, anticorps CG2, anticorps transmembrane protein 245, anticorps TMEM245
    Sujet

    C9orf5 (chromosome 9 open reading frame 5), also known as CG2, is a 911 amino acid multi-pass membrane protein that is widely expressed and exists as four alternatively spliced isoforms. The gene encoding C9orf5 maps to human chromosome 9, which consists of about 145 million bases, represents 4 % of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

    Subcellular location: Cell membrane

    Synonyms: C9orf5, TM245_HUMAN, Protein CG-2, Transmembrane protein C9orf5,

    ID gène
    23731
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