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SCUBE3 anticorps (AA 451-550) (HRP)

SCUBE3 Reactivité: Humain IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1712383
  • Antigène Voir toutes SCUBE3 Anticorps
    SCUBE3 (Signal Peptide, CUB Domain, EGF-Like 3 (SCUBE3))
    Épitope
    • 14
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 451-550
    Reactivité
    • 32
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 29
    • 3
    Lapin
    Clonalité
    • 30
    • 2
    Polyclonal
    Conjugué
    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SCUBE3 est conjugé à/à la HRP
    Application
    • 17
    • 14
    • 13
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SCUBE3
    Isotype
    IgG
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C/-80 °C
    Stockage commentaire
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Date de péremption
    12 months
  • Antigène
    SCUBE3 (Signal Peptide, CUB Domain, EGF-Like 3 (SCUBE3))
    Autre désignation
    SCUBE3 (SCUBE3 Produits)
    Synonymes
    anticorps CEGF3, anticorps D030038I21Rik, anticorps signal peptide, CUB domain and EGF like domain containing 3, anticorps signal peptide, CUB domain, EGF-like 3, anticorps signal peptide, CUB and EGF-like domain-containing protein 3, anticorps SCUBE3, anticorps scube3, anticorps Scube3, anticorps LOC100152993
    Sujet

    SCUBE3 is a novel secreted 993 amino acid cell-surface osteoblast protein that plays an important role in bone cell biology. While highly expressed in osteoblasts, SCUBE3 expression is unobservable or very low in non-bone tissues. SCUBE3 forms homo-oligomers and hetero-oligomers with SCUBE1, and may undergo C-terminal proteolytic cleavage or become N-glycosylated following translation. Two SCUBE3 isoforms exist as a result of alternative splicing events. SCUBE3 contains one CUB domain and nine EGF-like domains, and is encoded by a gene which maps to human chromosome 6p21.31, a region associated with a rare form of metabolic bone disease known as Paget's disease. Chromosome 6 contains 170 million base pairs and comprises nearly 6 % of the human genome.

    Subcellular location: Secreted, Cell membrane, Extracellular matrix

    Synonyms: CEGF3, CUB and EGF containing protein 3, CUB and EGF-like domain-containing protein 3, CUB domain and EGF like repeat containing 3, DKFZp686B09105, DKFZp686B1223, DKFZp686D20108, FLJ34743, OTTHUMP00000016250, SCUB3_HUMAN, SCUBE 3, SCUBE3, Signal peptide, Signal peptide CUB and EGF like domain containing protein 3, Signal peptide CUB domain EGF like 3.

    ID gène
    222663
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