Inhibin alpha anticorps (AA 301-366)

N° du produit ABIN1713642

Détail du produit anti-Inhibin alpha anticorps

Antigène: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Épitope: AA 301-366

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Inhibin alpha est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Monkey

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Inhibin Alpha

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Inhibin alpha

Antigène: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Autre désignation: Inhibin Alpha (INHA Produits)

Synonymes: anticorps si:dkey-91f15.2, anticorps INHA, anticorps MGC108500, anticorps AW555078, anticorps inhibin, alpha, anticorps inhibin alpha subunit, anticorps inhibin alpha, anticorps inhibin alpha L homeolog, anticorps inha, anticorps INHA, anticorps inha.L, anticorps Inha

Sujet:

Synonyms: A inhibin subunit precursor, IHA, INHA, Inhibin alpha chain, Inhibin alpha chain precursor, Inhibin alpha subunit, INHA_HUMAN.

Background: The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.

ID gène: 3623

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion