ASPSCR1 anticorps (AA 351-420)

N° du produit ABIN1713923

Détail du produit anti-ASPSCR1 anticorps

Antigène: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Épitope: AA 351-420

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASPSCR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Réactivité croisée: Souris, Rat

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TUG/ASPC

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ASPSCR1

Antigène: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Autre désignation: TUG/ASPC (ASPSCR1 Produits)

Synonymes: anticorps tug, anticorps aspl, anticorps asps, anticorps rcc17, anticorps ubxd9, anticorps aspcr1, anticorps ASPCR1, anticorps ASPL, anticorps ASPS, anticorps RCC17, anticorps TUG, anticorps UBXD9, anticorps UBXN9, anticorps 1190006K01Rik, anticorps ASPC, anticorps ASPSCR1, UBX domain containing tether for SLC2A4, anticorps alveolar soft part sarcoma chromosome region, candidate 1 S homeolog, anticorps alveolar soft part sarcoma chromosome region, candidate 1, anticorps alveolar soft part sarcoma chromosome region, candidate 1 (human), anticorps ASPSCR1, anticorps aspscr1.S, anticorps Aspscr1, anticorps aspscr1, anticorps Bm1_55980

Sujet:

Synonyms: Alveolar soft part sarcoma chromosomal region candidate gene 1 protein, Alveolar soft part sarcoma chromosome region candidate 1 human, Alveolar soft part sarcoma locus, ASPC, ASPC1_HUMAN, ASPCR 1, ASPCR1, ASPL, ASPS, ASPSCR 1, Aspscr1, FLJ45380, RCC 17, RCC17, renal cell carcinoma gene on chromosome 17, renal cell carcinoma papillary 17, Renal papillary cell carcinoma protein 17, Tether containing a UBX domain for GLUT4, Tether containing UBX domain for GLUT4, TUG, UBX domain containing protein 9, UBX domain protein 9, UBX domain-containing protein 9, UBXD 9, UBXD9, UBXN 9, UBXN9.

Background: Glut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity. TUG (ASPL in humans) regulates the trafficking of glucose via Glut4. Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin. TUG acts by trapping endocytosed Glut4 and tethering it intracellularly. Insulin mobilizes this pool of retained Glut4 by releasing the tether.

ID gène: 79058