AIRE anticorps (Internal Region)
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- Antigène Voir toutes AIRE Anticorps
- AIRE (Autoimmune Regulator (AIRE))
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Épitope
- Internal Region
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Reactivité
- Humain, Rat, Chien, Boeuf (Vache)
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp AIRE est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- Reacts with human AIRE
- Réactivité croisée
- Boeuf (Vache), Chien, Rat (Rattus)
- Réactivité croisée (Details)
- This antibody is expected to recognise isoform 1 (NP_000374.1) only. Cross reacts with bovine, canine and rat protein.
- Purification
- Antigen affinity purified
- Immunogène
- Synthetic peptide C-KDVDLSQPRKGRKP from an internal region of human AIRE (NP_000374.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Rat (100%), Horse (100%), Dog (100%), Hamster (100%), Elephant (100%)
- Top Product
- Discover our top product AIRE Anticorps primaire
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- Indications d'application
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Working dilution: ELISA (1:32000), IHC-P (2.5 μg/mL), WB (0.5 - 1 μg/mL)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- TBS, pH 7.3, BSA 0.5 % , Sodium azide 0.02 %
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Minimize freezing and thawing.
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- Antigène
- AIRE (Autoimmune Regulator (AIRE))
- Autre désignation
- AIRE (AIRE Produits)
- Synonymes
- anticorps AIRE1, anticorps APECED, anticorps APS1, anticorps APSI, anticorps PGA1, anticorps autoimmune regulator, anticorps autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy), anticorps AaeL_AAEL013794, anticorps CpipJ_CPIJ001208, anticorps CpipJ_CPIJ001209, anticorps AIRE, anticorps Aire
- Sujet
- Transcriptional regulator that binds to DNA as a dimer or as a tetramer, but not as a monomer. Binds to G-doublets in an A/T-rich environment, the preferred motif is a tandem repeat of 5'-. ATTGGTTA-3' combined with a 5'-TTATTA-3' box. Binds to nucleosomes
- UniProt
- O43918
- Pathways
- Chromatin Binding
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