ARC (AA 191-208) anticorps
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- Antigène
- ARC
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Épitope
- AA 191-208
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Inconjugué
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- Reacts with human ARC.
- Purification
- Purified
- Immunogène
- Peptide corresponding to aa 191-208 of human ARC.
- Isotype
- IgG
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- Indications d'application
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC (5 μg/mL) WB(1 - 10 μg/mL) - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Dilute in PBS or medium that is identical to that used in the assay system.
- Stock
- -20 °C
- Stockage commentaire
- Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ARC
- Synonymes
- anticorps activity regulated cytoskeleton associated protein, anticorps Arc
- Sujet
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A novel CARD domain-containing protein was recently identified and designated ARC (apoptosis repressor with CARD). ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.
Nucleolar protein 3 Apoptosis repressor with CARD Muscle-enriched cytoplasmic protein, Myp Nucleolar protein of 30 kDa, Nop30 Gene name: NOL3, NOP - ID gène
- 8996
- UniProt
- O60936
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