ARC (AA 2-18) anticorps

N° du produit ABIN1731926

Détail du produit

Antigène: ARC

Épitope: AA 2-18

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Specificité: Reacts with the human, mouse, and rat ARC.

Purification: Purified

Immunogène: Peptide corresponding to aa 2-18 of human ARC.

Isotype: IgG

Information d'application

Indications d'application: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(2 μg/mL)

Positive control: HeLa cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Dilute in PBS or medium that is identical to that used in the assay system.

Stock: -20 °C

Stockage commentaire: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: ARC

Synonymes: anticorps activity regulated cytoskeleton associated protein, anticorps Arc

Sujet: A novel CARD domain-containing protein was recently identified and designated ARC (apoptosis repressor with CARD). ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The mRNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.

Nucleolar protein 3 Apoptosis repressor with CARD Muscle-enriched cytoplasmic protein, Myp Nucleolar protein of 30 kDa, Nop30 Gene name: NOL3, ARC, NOP, FCM,

ID gène: 8996

UniProt: O60936