pADPR anticorps (Agarose Beads)

N° du produit ABIN1741705

Détail du produit

Antigène: pADPR

Reactivité: Toutes les espèces

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Agarose Beads

Application: Immunoprecipitation (IP)

Attributs du produit: Recognizes DNA-damage and apoptosis related poly-ADP ribosylated proteins and poly (ADP-ribose) polymer

Purification: Protein A affinity column

Immunogène: poly(ADP-ribose)

Clone: 10H

Isotype: IgG3

Information d'application

Indications d'application: 0.5 µg/IP reaction

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4 with 0,05 % sodium azides

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze/thaw cycles.

Stock: 4 °C

Stockage commentaire: Stable for 1 year from date of shipment when stored at -20 °C or -70 °C. Stable for at least 1 month at 4 °C.

Référence

Kanai, Tong, Sugihara, Wang, Fukasawa, Miwa: "Involvement of poly(ADP-Ribose) polymerase 1 and poly(ADP-Ribosyl)ation in regulation of centrosome function." dans: Molecular and cellular biology, Vol. 23, Issue 7, pp. 2451-62, (2003) (PubMed).

Détail du antigène

Antigène: pADPR

Sujet: Synonyms: poly(ADP-ribose)
Poly(ADP-ribose) or pADPr is a polymer synthesized by a class of enzymes named poly(ADP-ribose) polymerase (PARP). Using NAD+ as substrate, PARP catalyzes the formation of the polymer pADPr, with chain lengths ranging from 2 to 300 residues, containing approximately 2 % branching in the chain. pADPr becomes attached to nuclear proteins, and to PARP itself (automodification).