CLEC10A anticorps

N° du produit ABIN181065

Détail du produit anti-CLEC10A anticorps

Antigène: CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CLEC10A est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This antibody recognizes murine CD301, a 38 kDa cell surface protein that is otherwise known as macrophage galactose N-acetylgalactosamine lectin (MGL) or dendritic cell asialoglycoprotein (DC-ASGPR). Clone ER-MP23 is reported to block the function of mouse CD301. The antibody binds both MGL1 and MGL2 homologues.

Réactivité croisée (Details): Species reactivity (tested):Mouse.

Attributs du produit: Synonyms: CLECSF13, CLECSF14, HML, C-type lectin domain family 10 member A, C-type lectinsuperfamily member 14, Macrophage lectin 2

Purification: Affinity Chromatography on Protein G

Immunogène: Balb/c macrophage precursor cell hybrids. Cells from immunised rats were fused with cells of the rat Y3-Ag1. 2. 3 myeloma cell line. Genename: CD301

Clone: ER-MP23

Isotype: IgG2a

Information d'application

Indications d'application: Immunohistochemistry on Frozen Sections. Flow Cytometry: Use 10 μL of 1/100-1/200 diluted antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CLEC10A

Antigène: CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))

Autre désignation: CD301 / CLEC10A (CLEC10A Produits)

Synonymes: anticorps CLEC10A, anticorps CD301, anticorps CLECSF13, anticorps CLECSF14, anticorps HML, anticorps HML2, anticorps MGL, anticorps CD301a, anticorps M-ASGP-BP-1, anticorps Mgl, anticorps Mgl1, anticorps Mgll, anticorps C-type lectin domain family 10 member A, anticorps C-type lectin domain containing 10A, anticorps C-type lectin domain family 10, member A, anticorps LOC607405, anticorps CLEC10A, anticorps Clec10a

Sujet: In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Expression of CD301 is induced by alternative (i.e. IL-4/IL-13 mediated) activation of macrophages and dendritic cells, but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated.Synonyms: C-type lectin domain family 10 member A, C-type lectin superfamily member 14, CLECSF13, CLECSF14, HML, Macrophage lectin 2

ID gène: 10462

UniProt: Q8IUN9