EGFR anticorps (Extracellular Domain) (PE)

N° du produit ABIN181809

Cet anticorps anti-EGFR est un anticorps Rat Monoclonal détectant EGFR dans FACS. Adapté pour Humain.

Aperçu rapide pour EGFR anticorps (Extracellular Domain) (PE) (ABIN181809)

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp EGFR est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: ICR10

Détail du produit anti-EGFR anticorps (PE)

Épitope: Extracellular Domain

Specificité: This antibody recognises the epidermal growth factor receptor (EGFR). This antibody binds to epitope B from EGFR (1, 2).Aff. Const.:6.7 x 10e-9 M

Purification: Affinity chromatography on Protein G

Immunogène: Extracellular domain of human EGF-receptor from head and neck carcinoma.

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1.0 mL distilled water

Buffer: PBS containing 1 % BSA and 5 % Bovine Serum Albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur EGFR

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Autre désignation: EGFR / ERBB1

Sujet: EGFR is over expressed in a high proportion of breast cancer cells and in a range of other carcinomas. High level expression of EGFR is often associated with advanced disease and poor prognosis.Synonyms: EGF Receptor, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, c-ErbB-1, erbB-1

ID gène: 1956

NCBI Accession: NP_005219

UniProt: P00533

Pathways: Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins