SOS1 anticorps

N° du produit ABIN1819949

L’anticorps Souris Monoclonal anti-SOS1 a été validé pour WB, ELISA et IF. Il convient pour détecter SOS1 dans des échantillons de Humain, Souris, Rat, Cheval, Lapin, Boeuf (Vache), Singe, Cobaye et Porc.

Aperçu rapide pour SOS1 anticorps (ABIN1819949)

Antigène: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Reactivité: Humain, Souris, Rat, Cheval, Lapin, Boeuf (Vache), Singe, Cobaye, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SOS1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: SOS-1

Détail du produit anti-SOS1 anticorps

Specificité: Recognizes SOS1 (son of sevenless homolog 1), a ubiquitously expressed 150kD intracellular protein and bifunctional guanine nucleotide exchange factor (GEF), which plays a role in growth and differentiation signalling pathways and in actin reorganization, by acting as a regulator of Ras and Rac/Rho GTPases. Mutations in the SOS1 gene are responsible for the rare oral overgrowth condition known as gingival fibromatosis 1 (GINGF1), and also the cause of the relatively common autosomal dominant disorder Noonan syndrome type 4 (NS4), characterized by short stature, congenital heart malformation, bleeding diathesis and distinctive facial features.

Purification: Protein A purified

Immunogène: Synthetic peptide corresponding to amino acids THPSMHRDGPPLLENAHSS of human SOS1. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Ferret, Elephant, Panda, Bovine, Cat, Horse, Rabbit, Opossum, Guinea pig (100%), Dog, Turkey, Zebra finch (95%), Lizard (89%).

Type of Immunogen: Synthetic peptide

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, IF, WB (1 μg/mL)

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur SOS1

Antigène: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Autre désignation: SOS1 / HGF

Sujet: Name/Gene ID: SOS1

Synonyms: SOS1, GINGF, NS4, SOS-1, Son of sevenless homolog 1, GF1, GGF1

ID gène: 6654

Pathways: Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling